Methylation, Ltd., offers a number of different kits that focus on DNMT and DNMT/DNA interactions. Here is a summary:

ICM kits: These are DNMT isoform specific kits that measure endogenous binding of DNMT (1,1b, 2,3a,3b) to genomic DNA. This is equivalent to a methylase based footprinting experiment and is described in detail by Liu et al., (2003). A summary of the ICM kit is available on-line as well: ICM Summary page.



Mailing address:
Methylation, Ltd.
108 Aces Alley
Port Orange, FL
T. 386-304-5948
F. 614-559-3932

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